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Mal-PEG4-Val-Cit-PAB-PNP

Product Name
Mal-PEG4-Val-Cit-PAB-PNP
CAS No.
2112738-09-5
Chemical Name
Mal-PEG4-Val-Cit-PAB-PNP
Synonyms
Mal-PEG4-Val-Cit-PAB-PNP;4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl (4-nitrophenyl) carbonate;4-((17S,20S)-1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosan-21-amido)benzyl (4-nitrophenyl) carbonate;L-Ornithinamide, N-[15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
CBNumber
CB23373644
Molecular Formula
C40H53N7O15
Formula Weight
871.89
MOL File
2112738-09-5.mol
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Mal-PEG4-Val-Cit-PAB-PNP Property

solubility 
Soluble in DMSO, DMF
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23668
Product name
Mal-PEG4-Val-Cit-PAB-PNP
Purity
97%
Packaging
100mg
Price
$950
Updated
2021/12/16
Iris Biotech GmbH
Product number
ADC1210
Product name
Mal-PEG(4)-Val-Cit-PAB-PNP
Packaging
100mg
Price
$1012.5
Updated
2021/12/16
Ambeed
Product number
A763179
Product name
4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl(4-nitrophenyl)carbonate
Purity
95%
Packaging
100mg
Price
$1242
Updated
2021/12/16
Ambeed
Product number
A763179
Product name
4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl(4-nitrophenyl)carbonate
Purity
95%
Packaging
250mg
Price
$2110
Updated
2021/12/16
Ambeed
Product number
A763179
Product name
4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl(4-nitrophenyl)carbonate
Purity
95%
Packaging
1g
Price
$5485
Updated
2021/12/16
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Mal-PEG4-Val-Cit-PAB-PNP Chemical Properties,Usage,Production

Description

Mal-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker. The Val-Cit linkers can be cleaved by Cathepsin B. Maleimide (Mal) group is reactive toward thiol groups. PEG space improve compound's aqueous solubility. PNP is a good leaving group.

Biological Activity

Mal-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize antibody drug conjugates (ADC).

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

Mal-PEG4-Val-Cit-PAB-PNP Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG4-Val-Cit-PAB-PNP Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52927
Advantage
58
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View Lastest Price from Mal-PEG4-Val-Cit-PAB-PNP manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Mal-PEG4-Val-Cit-PAB-PNP 2112738-09-5
Price
US $0.00/mg
Min. Order
100mg
Purity
>98.00%
Supply Ability
100mg
Release date
2024-03-29

2112738-09-5, Mal-PEG4-Val-Cit-PAB-PNPRelated Search:


  • Mal-PEG4-Val-Cit-PAB-PNP
  • L-Ornithinamide, N-[15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
  • 4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl (4-nitrophenyl) carbonate
  • 4-((17S,20S)-1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosan-21-amido)benzyl (4-nitrophenyl) carbonate
  • 2112738-09-5
  • C40H53N7O15
  • Linker
  • ADC LINKER